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Hydrocortisone / Benzoyl Peroxide

Published: July 26, 2026Updated: August 25, 2026

Vanoxide-HC is a topical prescription medication used to treat inflammatory acne. It combines benzoyl peroxide, which helps reduce acne-causing bacteria, with hydrocortisone, a mild corticosterisone that helps reduce redness and swelling. This combination addresses both the bacterial and inflammatory components of acne lesions.

Quick summary

Topical acne treatment combining an antibacterial agent with an anti-inflammatory to treat inflammatory acne.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
220750
Generic
Vanoxide-Hc
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Vanoxide-HC is indicated for the topical treatment of inflammatory acne vulgaris, helping to reduce papules, pustules, and red inflamed lesions associated with acne.

Benzoyl peroxide works as a keratolytic and antibacterial agent to reduce acne bacteria and clear pores, while hydrocortisone provides anti-inflammatory relief to reduce redness and swelling at the application site.

Vanoxide-HC is for external use only on the skin. Common side effects may include dryness, irritation, or peeling at the application site. It may bleach hair or fabrics. Patients with known hypersensitivity to any ingredients should not use this product. Sun exposure should be minimized during treatment.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy