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Varicella Zoster Immune Globulin

Published: July 26, 2026Updated: August 25, 2026

Varizig is a brand-name immune globulin product containing antibodies against the varicella-zoster virus (the virus that causes chickenpox and shingles). It is used for post-exposure prophylaxis in individuals at high risk for severe varicella infection who cannot receive varicella vaccine. This medication is typically administered to immunocompromised patients, pregnant women, or newborns exposed to the virus.

Quick summary

Varizig is a varicella-zoster immune globulin used to prevent chickenpox in high-risk individuals after exposure to the virus.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
1365975
Generic
Varizig
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Post-exposure prophylaxis of varicella (chickenpox) in high-risk individuals including immunocompromised patients, pregnant women, newborns whose mothers had varicella around delivery, and premature infants exposed to the virus.

Varizig contains varicella-zoster immune globulin (VZIG), which provides passive immunity by supplying antibodies against the varicella-zoster virus. These pre-formed antibodies help neutralize the virus and reduce the severity of infection when given shortly after exposure.

Varizig is administered by intramuscular injection and should be given as soon as possible after exposure, ideally within 10 days. It is not a substitute for varicella vaccination in those who can receive it. This product is derived from human plasma and carries potential risks associated with blood-derived products.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy