Enalapril / Hydrochlorothiazide
Vaseretic is a prescription combination medication containing enalapril (an ACE inhibitor) and hydrochlorothiazide (a diuretic) used to treat high blood pressure. The two active ingredients work together to lower blood pressure through complementary mechanisms: one relaxes blood vessels while the other reduces fluid volume.
Vaseretic is a combination blood pressure medication pairing an ACE inhibitor with a diuretic.
Key facts at a glance
- RxNorm
- 175128
- Generic
- Vaseretic
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Vaseretic is primarily prescribed for the treatment of hypertension (high blood pressure) in patients who require combination therapy to achieve adequate blood pressure control.
Enalapril, an ACE inhibitor, blocks the angiotensin-converting enzyme responsible for producing angiotensin II, a substance that constricts blood vessels. Hydrochlorothiazide, a thiazide diuretic, helps the kidneys eliminate excess sodium and water from the body, reducing blood volume. Together, these actions decrease blood pressure.
Common side effects may include dizziness, headache, cough, and fatigue. Vaseretic is contraindicated in pregnancy and should not be used with aliskiren in patients with diabetes. Patients should be monitored for kidney function and electrolyte levels during treatment. Alcohol may enhance blood pressure-lowering effects.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy