Phentolamine
Vazculep is a nasal decongestant spray containing phenylephrine that provides temporary relief from nasal congestion by constricting blood vessels in the nasal passages. It is used by adults and children to relieve stuffy nose caused by colds, allergies, or sinus inflammation. The medication offers rapid onset of action for short-term symptom management.
A nasal decongestant spray that relieves stuffy nose by constricting blood vessels in the nasal passages for temporary symptom relief.
Key facts at a glance
- RxNorm
- 1542381
- Generic
- Vazculep
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of nasal congestion associated with the common cold, hay fever, other upper respiratory allergies, and sinusitis. Provides short-term symptomatic relief of stuffy or runny nose.
Vazculep contains phenylephrine, an alpha-1 adrenergic receptor agonist. It works by constricting blood vessels (vasoconstriction) in the nasal mucosa, which reduces swelling and inflammation of the nasal passages, allowing for easier breathing.
Should not be used for more than 3 consecutive days due to risk of rebound congestion (rhinitis medicamentosa). Avoid use in patients with severe heart disease, uncontrolled hypertension, or narrow-angle glaucoma. May interact with monoamine oxidase inhibitors (MAOIs) and other medications. Consult a healthcare provider before use if pregnant, breastfeeding, or giving to children.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 29, 2026. · Read our editorial policy