Panitumumab
Vectibix (panitumumab) is a prescription brand-name medication classified as an epidermal growth factor receptor (EGFR) inhibitor. It is used to treat certain types of metastatic colorectal cancer in patients whose tumors have wild-type RAS genes.
Vectibix is an EGFR-targeting monoclonal antibody used to treat metastatic colorectal cancer with wild-type RAS genes.
Key facts at a glance
- RxNorm
- 675979
- Generic
- Vectibix
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Vectibix is indicated for the treatment of adult patients with wild-type RAS (KRAS and NRAS) metastatic colorectal cancer, either as monotherapy or in combination with chemotherapy regimens such as FOLFOX or FOLFIRI.
Vectibix is a fully human monoclonal antibody that binds specifically to EGFR on the surface of cancer cells. By blocking EGFR signaling, it inhibits tumor cell proliferation, survival, and metastasis.
Vectibix is administered as an intravenous infusion every two weeks. Common side effects include skin reactions (acneiform rash, dry skin), hypomagnesemia, fatigue, and diarrhea. RAS status must be confirmed before treatment, as it is not effective in patients with RAS-mutant tumors. Patients should avoid sun exposure and may need skin moisturizers and sunscreen. Infusion reactions can occur during or after administration.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 29, 2026. · Read our editorial policy