Calcipotriene
Vectical (calcitriol) is a topical vitamin D analog used to treat plaque psoriasis. As the active form of vitamin D3, it helps regulate skin cell growth and differentiation to reduce the scaling, thickness, and inflammation associated with psoriasis plaques. This prescription medication is applied directly to affected skin areas.
Vectical is a topical calcitriol ointment used to treat plaque psoriasis by regulating skin cell growth.
Key facts at a glance
- RxNorm
- 831894
- Generic
- Vectical
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Vectical is indicated for the topical treatment of mild to moderate plaque psoriasis vulgaris. It is typically prescribed when the condition affects localized areas of the skin.
Calcitriol, the active ingredient in Vectical, is the hormonally active form of vitamin D. It works by binding to vitamin D receptors in skin cells (keratinocytes), which helps normalize skin cell proliferation and differentiation. This reduces the excessive scaling and thickening of skin that occurs in psoriatic plaques.
Vectical is for external use only and should not be applied to the face. Avoid using more than the prescribed amount, as excessive application may lead to elevated calcium levels in the blood (hypercalcemia). Patients should minimize exposure to natural or artificial sunlight on treated areas. Common side effects may include skin discomfort, pruritus, and skin irritation at the application site.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy