Vericiguat
Verquvo (vericiguat) is a prescription medication for adults with chronic heart failure who have reduced ejection fraction. It works by stimulating an enzyme to relax and widen blood vessels, making it easier for the heart to pump blood and reducing cardiovascular death and hospitalization risk.
Verquvo is a heart failure medication that helps improve blood flow and reduce strain on the heart in patients with reduced ejection fraction.
Key facts at a glance
- RxNorm
- 2475847
- Generic
- Verquvo
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Verquvo is used to reduce the risk of cardiovascular death and hospitalization for heart failure in adults with chronic heart failure with reduced ejection fraction (HFrEF), particularly in patients who have been stabilized after a recent hospitalization or need for outpatient IV diuretics.
Verquvo is a soluble guanylate cyclase (sGC) stimulator. It directly stimulates sGC, an enzyme that produces cyclic guanosine monophosphate (cGMP), leading to smooth muscle relaxation, vasodilation, improved blood flow, and reduced cardiac workload.
Verquvo is contraindicated in pregnancy. Common side effects include hypotension and anemia. It is taken orally once daily with food and should be used in combination with other heart failure therapies. Patients should discuss all medications with their healthcare provider before starting treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy