Clozapine
Versacloz is a brand-name atypical antipsychotic medication containing clozapine, used to treat treatment-resistant schizophrenia in patients who have not responded adequately to other antipsychotic treatments. It works by modulating dopamine and serotonin receptors in the brain to help reduce psychotic symptoms. Due to the risk of serious blood side effects, patients require regular blood monitoring throughout treatment.
Versacloz is an atypical antipsychotic for treatment-resistant schizophrenia that requires regular blood monitoring due to risk of serious blood disorders.
Key facts at a glance
- RxNorm
- 1369826
- Generic
- Versacloz
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment-resistant schizophrenia in patients 18 years and older who have failed to respond adequately to at least two other antipsychotic medications. Not indicated for patients with uncontrolled epilepsy, history of drug-induced neutropenia, or severe central nervous system depression.
Versacloz contains clozapine, an atypical antipsychotic that works by blocking dopamine D4 receptors and serotonin 5-HT2 receptors. It has a lower affinity for dopamine D2 receptors compared to typical antipsychotics, which contributes to its reduced risk of extrapyramidal symptoms.
Requires regular absolute neutrophil count (ANC) monitoring due to risk of agranulocytosis. Must be dispensed with a Risk Evaluation and Mitigation Strategy (REMS) program. May cause seizures, orthostatic hypotension, myocarditis, and metabolic changes. Should not be stopped abruptly. Only available through restricted distribution programs.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy