Hydrocortisone
Vetoryl is a brand-name veterinary medication containing trilostane, used primarily to treat Cushing's disease (hyperadrenocorticism) in dogs. It works by reducing the production of cortisol from the adrenal glands, helping to manage the symptoms associated with this condition.
Vetoryl is a trilostane-based medication for treating Cushing's disease in dogs by reducing cortisol production.
Key facts at a glance
- RxNorm
- 861978
- Generic
- Vetoryl
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Vetoryl is primarily used to treat pituitary-dependent and adrenal-dependent hyperadrenocorticism (Cushing's disease) in dogs. It may also be used in some cases for feline Cushing's syndrome.
Vetoryl contains trilostane, which inhibits the enzyme 3-beta-hydroxysteroid dehydrogenase. This enzyme is necessary for cortisol synthesis in the adrenal cortex, so blocking it reduces the overproduction of cortisol that characterizes Cushing's disease.
Vetoryl is a prescription-only medication that requires veterinary monitoring. Regular blood tests are needed to monitor cortisol levels and adjust dosage. It should not be used in pregnant animals or those with certain liver or kidney conditions. Potential side effects include lethargy, vomiting, diarrhea, and weakness. Always follow your veterinarian's dosing instructions carefully.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy