Hydrocodone / Ibuprofen
Vicoprofen is a brand-name combination medication that contains hydrocodone (an opioid pain reliever) and ibuprofen (an anti-inflammatory pain reliever). It is used to manage moderate to severe acute pain that requires opioid-level analgesia when other treatments are not sufficient.
Vicoprofen combines an opioid with an NSAID to treat short-term severe pain.
Key facts at a glance
- RxNorm
- 220826
- Generic
- Vicoprofen
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Management of acute pain severe enough to require opioid-level analgesia when other treatments have not been adequate.
Hydrocodone binds to opioid receptors in the brain to reduce pain perception, while ibuprofen inhibits prostaglandin synthesis to reduce inflammation and pain.
Contains an opioid (hydrocodone) with risk of dependence, addiction, and abuse. NSAIDs component carries risks of GI bleeding, cardiovascular events, and kidney problems. Use with CNS depressants increases serious respiratory depression risk. Not for use in children. Controlled substance with strict prescribing regulations.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy