Ribociclib
Vijoice (alpelisib) is a prescription medication used to treat adults and children with PIK3CA-Related Overgrowth Spectrum (PROS), a rare genetic condition causing abnormal tissue growth due to mutations in the PIK3CA gene. It works by inhibiting the PI3K enzyme pathway involved in cell growth and proliferation. This medication is specifically indicated for patients who require systemic therapy for their condition.
Vijoice is a PI3K inhibitor used to treat the rare genetic condition PROS (PIK3CA-Related Overgrowth Spectrum) in patients requiring systemic therapy.
Key facts at a glance
- RxNorm
- 2598454
- Generic
- Vijoice
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Vijoice is indicated for the treatment of PIK3CA-Related Overgrowth Spectrum (PROS) in adults and children aged 2 years and older who require systemic therapy. PROS encompasses a range of rare disorders characterized by overgrowth and malformations caused by PIK3CA gene mutations.
Vijoice contains alpelisib, a phosphoinositide 3-kinase (PI3K) inhibitor. It works by blocking the activity of the PI3K enzyme, which is part of a signaling pathway that promotes abnormal cell growth and proliferation. By inhibiting this pathway, the medication helps reduce the overgrowth of tissues characteristic of PROS.
Vijoice may cause serious side effects including hyperglycemia (high blood sugar), skin reactions, and diarrhea. Patients should have their blood glucose monitored regularly during treatment. The medication should not be used during pregnancy as it may harm an unborn baby. Patients should discuss all current medications with their healthcare provider to avoid interactions.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy