Vildagliptin
Vildagliptin is an oral DPP-4 inhibitor used to manage blood sugar levels in adults with type 2 diabetes by preventing the breakdown of incretin hormones.
Vildagliptin is a DPP-4 inhibitor used to control blood sugar in type 2 diabetes, either alone or with other antidiabetic drugs.
Key facts at a glance
- ATC
- A10BH02
- RxNorm
- 596554
- Generic
- Vildagliptin
- Class
- atc-a10
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of type 2 diabetes mellitus in adults to achieve glycemic control when diet and exercise are inadequate. May be used as monotherapy or as add-on therapy in combination with metformin, sulfonylureas, thiazolidinediones, or insulin when single-agent therapy is insufficient.
Vildagliptin inhibits the enzyme dipeptidyl peptidase-4 (DPP-4), which normally breaks down incretin hormones. By preventing this breakdown, it increases levels of active GLP-1 and GIP, hormones that stimulate insulin release and suppress glucagon in a glucose-dependent manner, thereby lowering blood sugar levels.
Not indicated for type 1 diabetes or diabetic ketoacidosis. Use with caution in patients with renal impairment, heart failure, or history of pancreatitis. May cause side effects such as headache, dizziness, or gastrointestinal symptoms. Always follow prescribed dosing and dietary/exercise recommendations.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy