Vinblastine
Vinblastine is a chemotherapy medication classified as a vinca alkaloid that works by inhibiting microtubule formation in cells, preventing them from dividing and multiplying. It is used to treat various cancers including Hodgkin's lymphoma, non-Hodgkin lymphoma, testicular cancer, and Kaposi's sarcoma, typically as part of combination chemotherapy regimens.
Vinblastine is a chemotherapy drug used to treat certain cancers by preventing cell division through microtubule inhibition.
This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.
Key facts at a glance
- ATC
- L01CA01
- RxNorm
- 11198
- Generic
- Vinblastine
- Class
- atc-l01
- Brands
- —
- Availability
- rx
- Pregnancy
- D
- Lactation
- unsafe
- Routes
- —
- Forms
- solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Vinblastine is primarily used to treat Hodgkin's lymphoma, non-Hodgkin lymphoma, testicular cancer, bladder cancer, breast cancer, and Kaposi's sarcoma. It may be used in combination with other chemotherapy agents depending on the specific cancer type and treatment protocol.
Vinblastine binds to tubulin and inhibits the assembly of microtubules, which are essential structures for cell division. By preventing proper mitotic spindle formation, the drug arrests cancer cells in metaphase, ultimately leading to cell death.
Vinblastine must be administered exclusively by intravenous injection under close medical supervision—never administered intrathecally as this is fatal. Common side effects include bone marrow suppression (low blood counts), peripheral neuropathy, hair loss, and gastrointestinal symptoms. Patients should be monitored regularly for blood counts and liver function during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy