Vindesine
Vindesine is a vinca alkaloid chemotherapy medication used to treat certain cancers by inhibiting cell division. It is primarily indicated for acute lymphoblastic leukemia and has also been used in some other malignancies. The drug works by disrupting microtubule formation, which prevents cancer cells from dividing and multiplying.
Vindesine is a chemotherapy drug that inhibits cell division to treat certain cancers, primarily acute lymphoblastic leukemia.
Key facts at a glance
- ATC
- L01CA03
- RxNorm
- 11204
- Generic
- Vindesine
- Class
- atc-l01
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Vindesine is primarily used to treat acute lymphoblastic leukemia (ALL), particularly in patients who have become resistant to other treatments. It has also been used in the treatment of melanoma, breast cancer, and some squamous cell carcinomas.
Vindesine is a vinca alkaloid that works by binding to tubulin and inhibiting microtubule assembly. This prevents the formation of the mitotic spindle, which is essential for cell division, thereby arresting cancer cells in metaphase and preventing their proliferation.
Vindesine is administered intravenously by healthcare professionals. Common side effects include neurotoxicity (peripheral neuropathy), bone marrow suppression, and gastrointestinal effects. Like other vinca alkaloids, it requires careful monitoring and dose adjustments based on patient response and toxicity.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy