Hydroxyzine
Vistaril (hydroxyzine) is an antihistamine medication used primarily to treat anxiety and tension, allergic skin conditions, and to help manage nausea and vomiting. It works by blocking histamine receptors in the body and may also be used as a sedative before medical procedures.
Vistaril is an antihistamine used for anxiety, allergies, and nausea with sedative properties.
Key facts at a glance
- RxNorm
- 282519
- Generic
- Vistaril
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Vistaril is prescribed for anxiety disorders, allergic skin conditions (pruritus), nausea and vomiting, and as preoperative sedation. It may also help with alcohol withdrawal symptoms.
As an antihistamine, Vistaril blocks histamine H1 receptors, reducing allergic responses. It also has anxiolytic properties affecting the central nervous system, producing a calming effect.
Common side effects include drowsiness, dry mouth, and dizziness. Patients should avoid alcohol and operating machinery until they know how the medication affects them. It may interact with other CNS depressants. Not recommended during early pregnancy. Effectiveness for long-term anxiety treatment may be limited compared to other options.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy