Vitrase
Vitrase is an injectable enzyme medication containing hyaluronidase, which temporarily breaks down hyaluronic acid in connective tissue. It is used as an adjunct to improve the absorption and dispersion of other medications, fluids, or contrast agents when administered together.
Vitrase is an enzyme that helps other drugs absorb faster by breaking down hyaluronic acid in tissues.
Key facts at a glance
- RxNorm
- 582689
- Generic
- Vitrase
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used as an adjunct to increase dispersion and absorption of co-administered injectable medications, subcutaneous or intramuscular injections, and parenteral fluids. Also employed in subcutaneous urography to facilitate tissue diffusion of contrast media.
Contains the enzyme hyaluronidase, which depolymerizes hyaluronic acid—a polysaccharide that contributes to tissue viscosity. This temporarily loosens connective tissue, allowing better diffusion of co-administered substances through the extracellular matrix.
Should not be injected into acutely inflamed or infected areas. May increase systemic absorption of co-administered drugs, potentially enhancing both therapeutic and adverse effects. Allergic reactions, including anaphylaxis, have been reported. Only compatible with medications specifically approved for use with hyaluronidase.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy