Naltrexone
Vivitrol is an extended-release injectable medication containing naltrexone, used to treat alcohol dependence and prevent opioid relapse. It works as an opioid antagonist, blocking receptors to reduce cravings and the rewarding effects of substances. This medication is typically used as part of a comprehensive treatment program that includes counseling and support.
Monthly injectable medication used to treat alcohol dependence and prevent opioid relapse by blocking opioid receptors.
Key facts at a glance
- RxNorm
- 636556
- Generic
- Vivitrol
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of alcohol dependence and prevention of relapse to opioid dependence. It is used in patients who are able to abstain from opioids prior to treatment initiation.
Naltrexone is an opioid antagonist that binds to opioid receptors in the brain, blocking the effects of opioids and reducing alcohol cravings. It is administered as an extended-release depot injection, providing continuous medication delivery over approximately one month.
Must be opioid-free for 7-14 days before starting treatment to avoid precipitated withdrawal. May cause liver toxicity; regular monitoring recommended. Can cause injection site reactions. Does not eliminate the need for psychosocial support and counseling. Patients should be aware that blocking opioid effects may lead to accidental overdose if they attempt to override the blockade.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy