Dacomitinib
Vizimpro (dacomitinib) is a prescription brand-name medication used to treat adults with metastatic non-small cell lung cancer that has specific EGFR mutations (exon 19 deletions or exon 21 L858R substitution mutations). It belongs to a class of drugs called tyrosine kinase inhibitors that target cancer cell growth and spread.
Vizimpro is an EGFR inhibitor used for EGFR-mutated metastatic non-small cell lung cancer.
Key facts at a glance
- RxNorm
- 2058916
- Generic
- Vizimpro
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of metastatic non-small cell lung cancer (NSCLC) in patients with EGFR exon 19 deletion or exon 21 L858R substitution mutations, as detected by an FDA-approved test.
Vizimpro is an irreversible tyrosine kinase inhibitor that blocks epidermal growth factor receptor (EGFR) and HER family receptors, inhibiting downstream signaling pathways that drive cancer cell proliferation, survival, and metastasis.
Prior to treatment, patients must have confirmed EGFR mutations. Common side effects include diarrhea, skin rash, paronychia, and stomatitis. Serious risks include interstitial lung disease and hepatotoxicity. Requires monitoring of liver function tests during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy