Pexidartinib
Vonjo (pacritinib) is a prescription medication used to treat adults with myelofibrosis, a rare bone marrow disorder that affects normal blood cell production. It belongs to a class of drugs called Janus kinase (JAK) inhibitors and is specifically indicated for patients with thrombocytopenia (low platelet counts). Vonjo is an oral capsule that works by targeting abnormal signaling pathways involved in the disease process.
Vonjo is a JAK inhibitor used to treat myelofibrosis in patients with low platelet counts.
Key facts at a glance
- RxNorm
- 2595249
- Generic
- Vonjo
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Vonjo is used to treat intermediate or high-risk primary or secondary myelofibrosis in adult patients with thrombocytopenia (platelet count below 100,000/μL).
Vonjo is a Janus kinase inhibitor that blocks abnormal JAK signaling, which is overactive in myelofibrosis and contributes to inflammation and uncontrolled blood cell production in the bone marrow.
Vonjo may cause serious side effects including bleeding, infections, and cardiac events. It should not be used in patients with certain heart conditions or those taking specific medications. Regular blood monitoring is required during treatment. Patients should discuss their complete medical history and current medications with their healthcare provider before starting Vonjo.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy