Efgartigimod
Vyvgart is a prescription medication used to treat adults with generalized myasthenia gravis (gMG) who test positive for anti-acetylcholine receptor (AChR) antibodies. It works as an Fc receptor (FcRn) antagonist that helps reduce levels of pathogenic immunoglobulin G (IgG) antibodies that contribute to the disease. This medication is administered as an intravenous infusion in treatment cycles.
Vyvgart is used to treat generalized myasthenia gravis in AChR antibody-positive adults by reducing harmful IgG antibodies.
Key facts at a glance
- RxNorm
- 2587725
- Generic
- Vyvgart
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Vyvgart is indicated for the treatment of generalized myasthenia gravis (gMG) in adults who are anti-acetylcholine receptor (AChR) antibody positive, a chronic autoimmune neuromuscular disorder characterized by muscle weakness.
Vyvgart is an FcRn antagonist that binds to the neonatal Fc receptor (FcRn), which helps regulate IgG antibody levels. By blocking FcRn, the medication increases the degradation of IgG antibodies, including the pathogenic anti-AChR antibodies that attack the neuromuscular junction in myasthenia gravis.
Vyvgart is administered intravenously by a healthcare professional. Common side effects may include respiratory tract infections, headaches, and hypersensitivity reactions. Patients should be monitored for infections during treatment. Treatment cycles consist of weekly infusions for multiple weeks, with response evaluated between cycles. Patients should discuss their complete medical history with their healthcare provider before starting treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy