Diphenhydramine
Wal-Dryl is a brand-name antihistamine medication typically containing diphenhydramine, a first-generation antihistamine. It is commonly used to relieve symptoms of allergies, hay fever, and the common cold, such as sneezing, runny nose, itchy eyes, and skin rashes. Wal-Dryl products may also be marketed for temporary relief of occasional sleeplessness.
Wal-Dryl is an over-the-counter antihistamine used to treat allergy symptoms and may also serve as a temporary sleep aid.
Key facts at a glance
- RxNorm
- 1053139
- Generic
- Wal-Dryl
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Wal-Dryl is used to temporarily relieve symptoms associated with allergies, hay fever, and upper respiratory infections, including sneezing, runny nose, itchy/watery eyes, and itching of the skin or throat. Some Wal-Dryl products are also indicated for occasional sleeplessness.
The active ingredient diphenhydramine works by blocking histamine H1 receptors in the body, preventing histamine from causing allergic symptoms. It also has anticholinergic and sedative properties that contribute to its effects.
Wal-Dryl may cause drowsiness and should be used with caution when operating machinery or driving. Avoid alcohol and other CNS depressants while taking this medication. Not recommended for use in children under 6 years without medical advice. Consult a healthcare provider before use if pregnant, breastfeeding, or taking other medications.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy