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Diphenhydramine-D

Published: July 26, 2026Updated: August 26, 2026

Wal-Dryl-D is a brand-name over-the-counter medication typically used to temporarily relieve symptoms of allergies and the common cold, including sneezing, runny nose, itchy or watery eyes, and nasal congestion. It combines an antihistamine with a decongestant to address multiple allergy symptoms simultaneously. This medication is intended for use by adults and children as directed on the product label.

Quick summary

Wal-Dryl-D is an OTC antihistamine-decongestant combination that relieves allergy symptoms like sneezing, runny nose, and nasal congestion.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 26, 2026Editorial policy

Key facts at a glance

RxNorm
1087034
Generic
Wal-Dryl-D
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Temporarily relieves symptoms associated with hay fever, upper respiratory allergies, or the common cold, including sneezing, runny nose, itchy nose or throat, watery eyes, and nasal congestion.

Contains an antihistamine component that blocks the effects of histamine (a substance released during allergic reactions) and a decongestant component that helps shrink swollen nasal passages to relieve congestion.

Always follow package directions for proper dosing. Consult a healthcare provider before use if you have high blood pressure, heart disease, thyroid problems, diabetes, or are taking other medications. Do not use if you are currently taking a prescription monoamine oxidase inhibitor (MAOI). Stop use and contact a doctor if symptoms persist beyond 7 days or worsen. May cause drowsiness; avoid operating machinery or driving until you know how this medication affects you.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy