Rho(D) Immune Globulin
Winrho is a brand-name medication containing anti-D immunoglobulin used primarily to treat immune thrombocytopenic purpura (ITP) in certain patient populations, and to prevent Rh immunization in Rh-negative individuals exposed to Rh-positive blood. It works by providing passive immunity through anti-D antibodies.
Winrho is an anti-D immunoglobulin used to treat ITP and prevent Rh sensitization in at-risk patients.
Key facts at a glance
- RxNorm
- 220945
- Generic
- Winrho
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Winrho is primarily used to treat immune thrombocytopenic purpura (ITP), a bleeding disorder where the immune system destroys platelets. It is also used to prevent Rh immunization (Rh isoimmunization) in Rh-negative individuals who have been exposed to Rh-positive blood, such as during pregnancy with an Rh-positive fetus or after transfusion.
Winrho contains antibodies against the Rh(D) antigen on red blood cells. For ITP, the exact mechanism is not fully understood but is believed to involve antibody-coated red blood cells being cleared by the spleen, which reduces the overall immune destruction of platelets. For Rh prevention, the anti-D antibodies bind to Rh-positive red blood cells, preventing the recipient's immune system from mounting its own response against the Rh antigen.
Winrho is administered intravenously (IV) or intramuscularly (IM) by healthcare professionals. It is specific to Rh-negative patients and is not effective in Rh-positive individuals. Patients should be screened for their Rh status and may require blood typing before administration. Common side effects may include headache, chills, fever, and hemolysis. Winrho should not be used in patients with known IgA deficiency or severe hypersensitivity to human immune globulin products.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy