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Cenobamate

Published: July 26, 2026Updated: August 27, 2026

Xcopri (cenobamate) is a prescription brand-name antiepileptic medication used to treat focal (partial) seizures in adults. It is taken as an adjunctive therapy, meaning it is used alongside other seizure medications. The exact mechanism of action is not fully established but is thought to involve enhancement of GABAergic inhibition and reduction of sodium currents.

Quick summary

Xcopri is a brand-name seizure medication for adults with focal seizures, taken as adjunctive therapy.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
2265696
Generic
Xcopri
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Xcopri is indicated for the treatment of focal (partial) seizures in adults. It is used as adjunctive therapy when other antiepileptic medications alone are not adequately controlling seizures.

The exact mechanism of action is not fully specified. It is believed to work through enhancement of GABAergic inhibition and reduction of sodium channel currents, which helps reduce seizure activity in the brain.

Xcopri may cause serious or life-threatening reactions including drug reaction with eosinophilia and systemic symptoms (DRESS). Common side effects include drowsiness, dizziness, and fatigue. It may increase the risk of suicidal thoughts. Do not discontinue abruptly without medical supervision. Regular monitoring may be required during treatment.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy