Viloxazine
Xdemvy is an FDA-approved prescription eye drop medication used to treat ocular demodicosis, a condition caused by Demodex mites that infest the eyelashes and eyelids. The active ingredient lotilaner works as an ectoparasiticide, effectively killing these mites to reduce associated eyelid inflammation and collarette buildup. This treatment is specifically indicated for adult patients with collarettes (debris) associated with blepharitis due to Demodex mites.
Xdemvy is an FDA-approved prescription eye drop that treats ocular demodicosis (Demodex mite infestation) by killing the mites to reduce associated eyelid inflammation and debris buildup.
Key facts at a glance
- RxNorm
- 2644508
- Generic
- Xdemvy
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of collarettes associated with blepharitis caused by Demodex mites in adult patients. It is the first and only FDA-approved treatment specifically targeting ocular demodicosis.
Xdemvy contains lotilaner, an ectoparasiticide that targets the nervous system of parasites. Lotilaner causes paralysis and death of Demodex mites by disrupting their nerve function, eliminating the mite infestation on the eyelids and eyelashes.
Xdemvy is applied as an ophthalmic solution to the affected eye(s). The most common side effects include eye irritation, pain, and pruritus at the application site. Patients should follow prescribed dosing instructions and consult their healthcare provider if symptoms persist or worsen. Safety and efficacy in pediatric patients have not been established.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy