Minocycline
Xigduo is a combination prescription medication containing dapagliflozin and metformin, used to manage blood sugar levels in adults with type 2 diabetes. It is typically prescribed when diet, exercise, and single-agent therapy are insufficient for adequate glycemic control. This medication requires a prescription and should be used as part of a comprehensive diabetes management plan.
Xigduo is a combination diabetes medication used with diet and exercise to control blood sugar in adults with type 2 diabetes.
Key facts at a glance
- RxNorm
- 1592713
- Generic
- Xigduo
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Xigduo is indicated for improving glycemic control in adults with type 2 diabetes mellitus as an adjunct to diet and exercise. It is typically used when treatment with both dapagliflozin and metformin is appropriate, or when already taking these components separately.
Xigduo combines two mechanisms: dapagliflozin is an SGLT2 inhibitor that helps the kidneys remove glucose from the body through urine by blocking glucose reabsorption, while metformin is a biguanide that reduces the liver's glucose production and improves the body's insulin sensitivity.
Xigduo is not indicated for use in type 1 diabetes or diabetic ketoacidosis. Common side effects may include urinary tract infections, genital infections, and gastrointestinal symptoms. The medication may cause dehydration and hypotension, particularly when combined with diuretics. It should be discontinued prior to iodinated contrast imaging procedures and is not recommended for patients with severe kidney impairment. Lactic acidosis is a rare but serious risk associated with the metformin component.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy