Xipamide
Xipamide is a thiazide-like diuretic used to treat high blood pressure and fluid retention (edema) associated with conditions such as heart failure, kidney disorders, or liver cirrhosis. It works by helping the kidneys remove excess salt and water from the body through increased urine production, which reduces the workload on the heart and lowers blood pressure.
A diuretic medication that removes excess fluid from the body to treat high blood pressure and edema.
Key facts at a glance
- ATC
- C03BA10
- RxNorm
- 11371
- Generic
- Xipamide
- Class
- atc-c03
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Xipamide is primarily used to treat essential hypertension (high blood pressure) and edema associated with congestive heart failure, renal impairment, or hepatic cirrhosis.
As a thiazide-like diuretic, xipamide inhibits sodium reabsorption in the distal convoluted tubules of the kidney, promoting increased excretion of sodium, water, and electrolytes (particularly potassium) while reducing fluid volume and blood pressure.
Regular monitoring of electrolytes (especially potassium), renal function, and blood pressure is recommended. May cause hypokalemia, hyponatremia, or photosensitivity. Caution is advised in patients with gout, diabetes, or severe renal impairment. May interact with lithium, digoxin, and other antihypertensive agents.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy