Perflubutane
Xofluza (baloxavir marboxil) is an antiviral prescription medication used to treat acute, uncomplicated influenza (the flu) in patients 5 years of age and older who have experienced symptoms for no more than 48 hours. It is taken as a single oral dose and works by inhibiting a viral enzyme necessary for the influenza virus to replicate.
Xofluza is a single-dose antiviral medication for treating influenza when taken within 48 hours of symptom onset.
Key facts at a glance
- RxNorm
- 2100001
- Generic
- Xofluza
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Xofluza is indicated for the treatment of acute, uncomplicated influenza in patients 5 years and older who have had symptoms for 48 hours or less. It is not a substitute for annual flu vaccination and is not recommended for patients with severe influenza complications.
Xofluza contains the active ingredient baloxavir marboxil, which inhibits the cap-dependent endonuclease activity of the influenza virus. This enzyme is essential for viral transcription and replication, helping to reduce the viral load in the body.
Xofluza is available only by prescription and is not effective against bacterial infections. Common side effects may include diarrhea, bronchitis, nausea, and headache. Patients should discuss their complete medical history with their healthcare provider, especially any history of immune system disorders, before taking Xofluza.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy