Gilteritinib
Xospata (gilteritinib) is a prescription medication used to treat adults with acute myeloid leukemia (AML) that has returned or not responded to prior treatment and has a specific genetic mutation called FLT3. It belongs to a class of drugs known as FLT3 inhibitors, which work by targeting and blocking the activity of the FLT3 protein to help slow the growth of cancer cells.
Xospata is a targeted therapy for adults with FLT3-mutated acute myeloid leukemia that has not responded to or has returned after prior treatment.
Key facts at a glance
- RxNorm
- 2105812
- Generic
- Xospata
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Xospata is indicated for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with a FLT3 mutation, as detected by an FDA-approved test.
Xospata is a FLT3 tyrosine kinase inhibitor. It works by blocking the activity of the FLT3 receptor tyrosine kinase, which is mutated in certain AML cells. By inhibiting FLT3, the medication helps slow the growth and spread of cancer cells.
Xospata may cause serious side effects including differentiation syndrome, which can be life-threatening. Patients should be monitored for symptoms such as fever, difficulty breathing, and rapid weight gain. Regular blood tests and monitoring are required during treatment. Patients should inform their healthcare provider of all medications and health conditions before starting treatment.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy