Zafirlukast
Zafirlukast is a leukotriene receptor antagonist used to prevent asthma symptoms and improve breathing in patients with chronic asthma. It is typically prescribed as part of a maintenance regimen for adults and children, often alongside other asthma medications. This oral medication helps reduce inflammation and airway constriction associated with asthma.
Zafirlukast is an oral asthma maintenance medication that blocks leukotriene receptors to reduce airway inflammation and prevent asthma symptoms.
Key facts at a glance
- ATC
- R03DC01
- RxNorm
- 114970
- Generic
- Zafirlukast
- Class
- atc-r03
- Brands
- Accolate
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prophylactic and chronic treatment of asthma in adults and children aged 5 years and older. It is not indicated for acute asthma attacks and should not be used as a rescue inhaler替代.
Zafirlukast blocks cysteinyl leukotriene CysLT1 receptors, preventing leukotrienes from binding and causing airway inflammation, bronchoconstriction, and mucus production. This reduces asthma symptoms and improves airflow over time.
Must be taken consistently for full benefit; not a rescue medication. May cause liver enzyme elevations requiring monitoring. Avoid in patients with hepatic impairment or hypersensitivity to the drug. May interact with warfarin and other medications metabolized by CYP450 enzymes.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy