Streptozocin
Zanosar is a brand name for streptozocin, an antineoplastic agent used primarily in the treatment of metastatic pancreatic islet cell tumors. It works by alkylating DNA in cancer cells, disrupting their ability to replicate and grow.
Zanosar is a chemotherapy medication used to treat certain pancreatic neuroendocrine tumors.
Key facts at a glance
- RxNorm
- 220991
- Generic
- Zanosar
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primarily used to treat metastatic pancreatic islet cell carcinoma, including insulinoma and other neuroendocrine tumors of the pancreas.
As an alkylating agent, streptozocin works by transferring methyl groups to nucleic acids, causing DNA strand cross-linking and preventing DNA replication in rapidly dividing cancer cells.
Administered intravenously by healthcare professionals. Common side effects include nausea, vomiting, and liver toxicity. May cause severe hypoglycemia due to pancreatic beta cell toxicity. Requires regular monitoring of liver and kidney function during treatment. Should only be used under oncologist supervision.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy