Vemurafenib
Zelboraf (vemurafenib) is a prescription brand-name medication classified as a BRAF inhibitor. It is used to treat certain types of melanoma and other cancers that have a specific genetic mutation called BRAF V600E. This targeted therapy works by blocking the activity of the mutated BRAF protein to slow or stop cancer cell growth.
Zelboraf is a targeted cancer therapy for melanoma and other cancers with the BRAF V600E mutation.
Key facts at a glance
- RxNorm
- 1147224
- Generic
- Zelboraf
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of melanoma that cannot be removed by surgery or has spread to other parts of the body (metastatic) and tests positive for the BRAF V600E mutation. May also be used for other cancers with this specific genetic mutation.
Zelboraf is a BRAF kinase inhibitor that targets and blocks the activity of the mutated BRAF protein, which is overactive in certain cancer cells and drives their uncontrolled growth and division.
Requires genetic testing for the BRAF mutation before use. May cause skin reactions, photosensitivity, joint pain, and other side effects. Can affect liver function and may increase risk of certain cancers. Must be taken exactly as prescribed by an oncologist.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy