Naloxone
Zimhi is a brand-name naloxone nasal spray used to reverse opioid overdoses by blocking the effects of opioids on the body. It is indicated for the emergency treatment of suspected opioid overdose to restore breathing.
Zimhi is a naloxone nasal spray used to reverse life-threatening opioid overdoses in emergency situations.
Key facts at a glance
- RxNorm
- 2589614
- Generic
- Zimhi
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Zimhi is indicated for the emergency treatment of opioid overdose, including respiratory depression caused by natural or synthetic opioids. It is used when opioid overdose is suspected based on symptoms such as decreased breathing or loss of consciousness.
Zimhi contains naloxone, an opioid antagonist that works by competitively binding to opioid receptors in the brain and spinal cord, displacing opioids and rapidly reversing their effects, including potentially fatal respiratory depression.
Zimhi is for emergency use only and does not replace professional medical care. After administration, seek immediate emergency medical attention even if the person awakens. It has no potential for abuse and no effect in people without opioids in their system. Available by prescription.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy