Zinc Chloride
Zinc Chloride is an essential trace element supplement used as an additive in parenteral nutrition and IV solutions to prevent or treat zinc deficiency. It is administered to patients who cannot receive adequate zinc through oral intake, such as those on long-term intravenous nutrition or with malabsorption conditions.
Zinc Chloride provides essential zinc supplementation for patients with deficiencies, particularly those requiring parenteral nutrition.
Key facts at a glance
- ATC
- B05
- RxNorm
- unknown
- Generic
- Zinc Chloride
- Class
- atc-b05
- Brands
- Bucalsep
- Availability
- otc
- Pregnancy
- A
- Lactation
- safe
- Half-life (h)
- 1
- Onset (min)
- 5
- Duration (h)
- 2
- Routes
- oral, topical
- Forms
- mouthwash, solution
- Regions
- Spain, Europe
- Monitoring
- none
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 500mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 250mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 400mg daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
7 groupspregnancy
first trimesteruse only if clearly needed
avoid use during pregnancy unless benefits outweigh risks, consult healthcare provider
regular prenatal monitoring
Use with caution and monitor for adverse effects.
pregnancy
second third trimesteruse only if clearly needed
avoid prolonged use, consult healthcare provider before use
regular prenatal monitoring
Use with caution and monitor for adverse effects.
lactation
breastfeedingno adjustment typically needed
avoid breast-feeding immediately after use, wait at least 30 minutes
monitor infant for gastrointestinal disturbances
Use with caution and monitor for adverse effects.
pediatric_age
children under 12use with caution
not recommended for children under 6 years, supervise use in older children to prevent accidental ingestion
monitor for signs of zinc toxicity
Use with caution and monitor for adverse effects.
geriatric
elderly over 65no adjustment typically needed
use as directed, may have increased mucosal sensitivity
regular oral examination
renal_impairment
mild to moderate renal impairmentmonitor for zinc accumulation with prolonged use
use with caution in patients with renal impairment, consider periodic monitoring of serum zinc levels
monitor serum zinc levels and renal function
Use with caution and monitor for adverse effects.
hepatic_impairment
mild to moderate hepatic impairmentno adjustment typically needed
no specific dosage adjustment needed for topical oral rinse
routine monitoring
Statistics and clinical data
Chemical formula
Molecular composition of Zinc Chloride
Medical applications
Approved uses in pharmaceutical formulations
Brand name
Brand name containing Zinc Chloride
Zinc deficiency prevention and treatment in patients receiving long-term parenteral nutrition, malabsorption syndromes, severe diarrhea, burns, and conditions requiring IV fluid therapy where zinc supplementation is medically necessary.
Zinc chloride dissociates into zinc and chloride ions when administered, providing bioavailable zinc that serves as a cofactor for over 300 enzymes involved in protein synthesis, immune function, wound healing, and nucleic acid metabolism.
Should be administered only under medical supervision with monitoring of zinc levels. Solution compatibility with other IV additives should be verified. Use with caution in patients with renal impairment. Local irritation at injection site may occur.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy