Zipsor
Zipsor is a brand-name NSAID containing diclofenac potassium, formulated as a liquid-filled softgel capsule designed for rapid absorption. It is primarily used to manage mild to moderate pain, including pain from osteoarthritis, rheumatoid arthritis, and menstrual cramps.
Zipsor is a fast-acting NSAID pain reliever commonly used for arthritis pain and menstrual discomfort.
Key facts at a glance
- RxNorm
- 858343
- Generic
- Zipsor
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Zipsor is indicated for the relief of mild to moderate pain associated with osteoarthritis, rheumatoid arthritis, and primary dysmenorrhea (menstrual pain). It may also be prescribed for other acute pain conditions as determined by a healthcare provider.
As an NSAID, Zipsor works by inhibiting cyclooxygenase (COX) enzymes, which reduces the production of prostaglandins—chemicals in the body that promote inflammation, pain, and fever. The liquid-filled capsule formulation allows for faster drug absorption compared to traditional tablet formulations.
Zipsor carries black box warnings for cardiovascular and gastrointestinal risks similar to other NSAIDs. It should not be used in patients at high risk of heart attack, stroke, or stomach bleeding. Common side effects include stomach upset, nausea, and dizziness. Use at the lowest effective dose for the shortest duration possible. Inform your doctor of any kidney problems, liver disease, or bleeding disorders before use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy