Zirabev
Zirabev is a prescription brand-name medication that is a biosimilar to Avastin (bevacizumab). It belongs to a class of drugs called vascular endothelial growth factor (VEGF) inhibitors and is used in combination with other medications to treat various types of cancer.
Zirabev is an oncology medication used to treat several types of cancer by inhibiting blood vessel growth to tumors.
Key facts at a glance
- RxNorm
- 2268040
- Generic
- Zirabev
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Zirabev is used to treat metastatic colorectal cancer, non-squamous non-small cell lung cancer, kidney cancer (renal cell carcinoma), ovarian cancer, fallopian tube cancer, peritoneal cancer, cervical cancer, and glioblastoma multiforme.
Zirabev is a monoclonal antibody that binds to vascular endothelial growth factor (VEGF), a protein that promotes blood vessel formation. By blocking VEGF, it inhibits the blood supply to tumors, helping to slow their growth and spread.
Zirabev is administered by intravenous infusion by a healthcare professional. It may cause serious side effects including bleeding, hypertension, proteinuria, wound healing complications, and gastrointestinal perforation. Patients should be monitored throughout treatment. This is a specialty medication that requires careful oversight by an oncology specialist.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy