Zituvimet
Zituvimet is a brand-name combination medication containing sitagliptin and metformin, used to manage blood sugar levels in adults with type 2 diabetes. This dual-therapy approach combines two different mechanisms to improve glycemic control when diet and exercise alone are insufficient.
Zituvimet is a diabetes medication combining sitagliptin and metformin to help control blood sugar in adults with type 2 diabetes.
Key facts at a glance
- RxNorm
- 2677156
- Generic
- Zituvimet
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Zituvimet is indicated for improving glycemic control in adults with type 2 diabetes mellitus, typically when monotherapy with either component has not provided adequate blood sugar management. It is used alongside diet and exercise.
The medication combines two agents: sitagliptin inhibits the DPP-4 enzyme to increase insulin release and decrease glucagon after meals, while metformin decreases hepatic glucose production and improves insulin sensitivity in muscle and fat tissues.
This medication is not indicated for type 1 diabetes or diabetic ketoacidosis. The metformin component carries a rare risk of lactic acidosis, particularly in patients with kidney impairment. Common side effects may include gastrointestinal symptoms. Dosing must be individualized and renal function should be assessed before starting therapy.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy