Vorinostat
Zolinza (vorinostat) is a histone deacetylase (HDAC) inhibitor used to treat cutaneous T-cell lymphoma (CTCL) when the disease persists, worsens, or returns after treatment with other medications. It is an oral medication that works by affecting gene expression and cell growth processes.
Zolinza is a prescription HDAC inhibitor used to treat certain types of cutaneous T-cell lymphoma in patients who have tried other treatments.
Key facts at a glance
- RxNorm
- 682524
- Generic
- Zolinza
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Zolinza is used to treat cutaneous T-cell lymphoma (CTCL) in patients with progressive, persistent, or recurrent disease following prior systemic therapy.
As an HDAC inhibitor, Zolinza blocks histone deacetylase enzymes, leading to accumulation of acetylated histones and other proteins, which can cause cell cycle arrest and apoptosis in cancer cells.
Common side effects include fatigue, nausea, diarrhea, and blood count changes. Patients should be monitored for blood clots, dehydration, and electrolyte abnormalities. Women of reproductive potential should use effective contraception during treatment. The medication should be taken with food and swallowed whole.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy