Sertraline

Zoloft is FDA-approved for the treatment of major depressive disorder (MDD), panic disorder, social anxiety disorder, post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), and obsessive-compulsive disorder (OCD). It may also be prescribed off-label for other conditions as determined by a healthcare provider.

Zoloft belongs to the class of medications called selective serotonin reuptake inhibitors (SSRIs). It works by blocking the reabsorption (reuptake) of serotonin in the brain, thereby increasing the availability of serotonin between neurons. This enhancement of serotonin signaling is believed to help improve mood, reduce anxiety, and alleviate other symptoms associated with various mental health conditions.

Zoloft is available only by prescription and should be taken exactly as directed by a healthcare provider. It may take several weeks to experience the full therapeutic effects. Common side effects may include nausea, insomnia, headache, and sexual dysfunction. Antidepressants, including Zoloft, may increase the risk of suicidal thoughts or behaviors in some individuals, particularly when starting treatment or adjusting dosage. Abruptly stopping Zoloft is not recommended; dosage should be gradually reduced under medical supervision. Patients should inform their doctor of all medications and health conditions before starting treatment.