Zopiclone
Zopiclone is a non-benzodiazepine hypnotic medication used for the short-term treatment of insomnia. It works by enhancing the effects of GABA, a calming neurotransmitter in the brain, to help induce and maintain sleep. This medication is typically prescribed when sleep difficulties significantly affect daily functioning and quality of life.
Zopiclone is a prescription sleep medication used for the short-term treatment of insomnia by enhancing GABA activity in the brain.
Key facts at a glance
- ATC
- N05CF01
- RxNorm
- 40001
- Generic
- Zopiclone
- Class
- atc-n05c
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Zopiclone is used to treat insomnia, including difficulty falling asleep, frequent nighttime awakenings, or early morning awakening. It is prescribed when sleep disturbances negatively impact daily functioning and well-being.
Zopiclone works by binding to and enhancing the activity of GABA-A receptors in the brain. This increases inhibitory signaling and produces a calming effect that helps facilitate the onset and maintenance of sleep.
Zopiclone should only be used short-term (typically 2-4 weeks maximum) due to risk of dependence and tolerance. Common side effects include drowsiness, dry mouth, bitter taste, and next-day sedation. It should be taken immediately before bedtime when you can dedicate 7-8 hours to sleep. Driving and operating machinery should be avoided until you know how the medication affects you. It is not recommended for use in children or during pregnancy.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy