Zorbium
Zorbium is a topical patch containing the local anesthetic bupivacaine, designed to be applied directly to the skin over painful areas. It is FDA-approved for the management of post-herpetic neuralgia, the chronic nerve pain that can persist after a shingles outbreak. The patch provides localized pain relief by delivering medication through the skin to the affected nerves.
Zorbium is a bupivacaine-containing topical patch used to relieve nerve pain following shingles.
Key facts at a glance
- RxNorm
- 2599847
- Generic
- Zorbium
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Zorbium is indicated for the management of post-herpetic neuralgia (PHN), the neuropathic pain that can develop in the area where a shingles (herpes zoster) rash occurred, often persisting for months or years after the rash heals.
The active ingredient bupivacaine is a long-acting local anesthetic that works by blocking sodium channels in nerve cells, thereby interrupting pain signal transmission. When applied as a topical patch, it delivers the medication directly to the painful area for localized relief.
Zorbium should only be applied to intact, dry skin and not to broken or inflamed skin. The patches should not be cut, and use should be limited to no more than 3 patches at a time. Common side effects may include application site reactions such as redness, itching, or irritation. Patients should consult their healthcare provider for proper application instructions and to discuss whether this treatment is appropriate for their individual condition.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 29, 2026. · Read our editorial policy