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Somatropin

Published: July 26, 2026Updated: August 29, 2026

Zorbtive (somatropin) is a recombinant human growth hormone used to treat short bowel syndrome in adults. It helps improve intestinal absorption of nutrients by promoting intestinal adaptation. This medication is typically used as part of a comprehensive treatment plan that includes specialized nutritional support and may be given with or without other medications.

Quick summary

Zorbtive is a growth hormone therapy for adults with short bowel syndrome that helps improve nutrient absorption through intestinal adaptation.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 29, 2026Editorial policy

Key facts at a glance

RxNorm
405411
Generic
Zorbtive
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Zorbtive is FDA-approved for the treatment of short bowel syndrome in adult patients. It is used when the patient requires ongoing nutritional support despite optimal dietary adjustments and supplement use.

Zorbtive contains somatropin, a recombinant growth hormone that promotes intestinal adaptation. It works by stimulating IGF-1 production in the intestines, which can increase villus height and enhance the absorptive surface area of the gut, thereby improving the body's ability to absorb nutrients and fluids.

Zorbtive is administered as a daily subcutaneous injection. Common side effects may include fluid retention, joint pain, and insulin resistance. Patients should be monitored for signs of pancreatitis or increased intracranial pressure. Treatment should be supervised by a healthcare provider experienced in managing short bowel syndrome.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 29, 2026. · Read our editorial policy