Everolimus
Zortress is an immunosuppressant medication containing everolimus used primarily to prevent organ rejection in patients who have received kidney or liver transplants. It is also prescribed for certain tumors associated with tuberous sclerosis complex and advanced kidney cancer.
Zortress is an immunosuppressant used to prevent organ rejection in transplant patients and treat certain tumors associated with tuberous sclerosis.
Key facts at a glance
- RxNorm
- 977428
- Generic
- Zortress
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevents organ rejection in kidney and liver transplant recipients; treats subependymal giant cell astrocytoma (SEGA) and renal angiomyolipoma associated with tuberous sclerosis complex; treats advanced renal cell carcinoma (a type of kidney cancer)
Belongs to a class of drugs called mTOR inhibitors; blocks the mammalian target of rapamycin (mTOR) protein involved in cell growth and proliferation, thereby suppressing immune system activity and inhibiting tumor cell growth
Patients taking Zortress are at increased risk for infections and certain cancers due to immunosuppression; common side effects include mouth ulcers, rash, and fatigue; requires regular blood monitoring; must be taken consistently with or without food as directed; avoid grapefruit juice as it may interact with the medication
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy