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Capsaicin

Published: July 26, 2026Updated: August 27, 2026

Zostrix Joint & Arthritis Pain Relief is a topical analgesic cream designed to provide temporary relief from minor aches and pains associated with muscles and joints, including arthritis. It contains capsaicin as its active ingredient, which is derived from chili peppers. This over-the-counter product is applied directly to the skin over painful areas.

Quick summary

A topical cream containing capsaicin that temporarily relieves minor arthritis and joint pain when applied to the skin.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
1796133
Generic
Zostrix Joint & Arthritis Pain Relief
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Temporarily relieves minor aches and pains of muscles and joints associated with arthritis, simple backache, strains, sprains, and bruises. Designed for adults and children 2 years of age and older.

Contains capsaicin, a natural compound derived from chili peppers. When applied topically, it works by depleting substance P from sensory nerve endings in the skin, which helps reduce pain signals sent to the brain.

For external use only. Avoid contact with eyes, mucous membranes, and broken or irritated skin. Wash hands thoroughly after application. A warming or burning sensation may occur upon initial use. If condition worsens or symptoms persist for more than 7 days, discontinue use and consult a healthcare provider.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy