Ganaxolone
Ztalmy (ganaxolone) is a prescription medication used to treat seizures associated with cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder, a rare genetic neurological condition. It belongs to a class of drugs called neuroactive steroids and is specifically indicated for patients 2 years of age and older.
Ztalmy is an antiseizure medication approved for treating seizures in patients with CDKL5 deficiency disorder.
Key facts at a glance
- RxNorm
- 2604695
- Generic
- Ztalmy
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Ztalmy is FDA-approved for the treatment of seizures associated with CDKL5 deficiency disorder (CDD), a rare genetic condition that causes severe developmental impairment and frequent seizures, in patients 2 years of age and older.
Ztalmy is a neuroactive steroid that works as a positive allosteric modulator of GABA-A receptors. It enhances the inhibitory effects of GABA, the brain's main calming neurotransmitter, which helps reduce seizure activity.
Ztalmy is taken as an oral suspension three times daily. Common side effects may include sleepiness, dizziness, and fatigue. Patients should avoid operating machinery until they know how the medication affects them. Treatment should be managed by a neurologist experienced in treating seizures.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy