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Buprenorphine/Naloxone

Published: July 26, 2026Updated: August 27, 2026

Zubsolv is a prescription medication combining buprenorphine and naloxone, designed for medication-assisted treatment of opioid use disorder. It is administered as a sublingual tablet that dissolves under the tongue, helping reduce opioid cravings and withdrawal symptoms while the naloxone component discourages misuse through injection.

Quick summary

Zubsolv is a sublingual medication containing buprenorphine and naloxone used to treat opioid dependence.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
1431077
Generic
Zubsolv
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of opioid use disorder (OUD) in adults. It is part of a complete treatment program that may include counseling and behavioral therapy.

Buprenorphine is a partial opioid agonist that binds to the same receptors as opioids but produces weaker effects, helping reduce cravings and withdrawal symptoms. Naloxone is an opioid antagonist that blocks opioid effects and discourages injection misuse.

Should be used as part of a comprehensive treatment plan under healthcare provider supervision. May cause dependence and withdrawal if stopped suddenly. Injection of this medication can precipitate severe withdrawal. Discuss all medical conditions and medications with your doctor before use.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy