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Tildrakizumab

Published: July 26, 2026Updated: August 27, 2026

Zuprevo (tildrakizumab) is a prescription brand-name medication used to treat moderate to severe plaque psoriasis in adults. It is a monoclonal antibody that works by targeting specific proteins in the immune system to reduce inflammation and skin cell overproduction associated with psoriasis.

Quick summary

Zuprevo is a biologic medication used to treat plaque psoriasis by reducing inflammation through immune system targeting.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
1366658
Generic
Zuprevo
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Zuprevo is indicated for the treatment of moderate to severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy.

Zuprevo is a monoclonal antibody that targets the p19 subunit of interleukin-23 (IL-23), a cytokine involved in the inflammatory response that contributes to psoriasis development.

As a biologic agent, Zuprevo is administered by injection and may increase risk of infections. Patients should be evaluated for tuberculosis before starting treatment and should not receive live vaccines during therapy. Common side effects may include upper respiratory infections, injection site reactions, and headaches.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy