Zuranolone
Zurzuvae (zuranolone) is a prescription medication approved for the treatment of postpartum depression (PPD) in adults. It is a neuroactive steroid that works by modulating GABA-A receptors in the brain, which may help restore hormonal balance and improve mood. Treatment is typically given as a short 14-day oral course.
Zurzuvae is a prescription medication for treating postpartum depression in adults, taken as a 14-day oral treatment that works by modulating brain receptors involved in mood regulation.
Key facts at a glance
- RxNorm
- 2669911
- Generic
- Zurzuvae
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Zurzuvae is FDA-approved for the treatment of postpartum depression (PPD) in adults. Postpartum depression is a serious mental health condition that can affect individuals following childbirth, characterized by symptoms such as persistent sadness, anxiety, exhaustion, and difficulty bonding with the baby.
Zurzuvae is a neuroactive steroid that acts as a positive allosteric modulator of GABA-A receptors in the brain. This mechanism may help address the dysregulation of neurosteroid levels that can occur during the postpartum period, potentially helping to reduce depressive symptoms.
Zurzuvae is taken once daily for 14 days. Common side effects may include drowsiness, dizziness, and sedation, so patients should avoid driving or operating machinery until they understand how the medication affects them. It should only be used under the guidance of a healthcare provider and is not recommended for use while breastfeeding without consulting a doctor. Patients should inform their healthcare provider about all medications they are taking, as drug interactions may occur.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy