Cetirizine
Zyrtec is a brand-name antihistamine medication containing cetirizine that provides relief from common allergy symptoms such as sneezing, runny nose, itchy or watery eyes, and itching due to hives or skin reactions. It is one of the most widely used over-the-counter allergy medications and is suitable for both adults and children.
Zyrtec is an over-the-counter antihistamine that relieves allergy symptoms like sneezing, itchy eyes, and runny nose with minimal drowsiness.
Key facts at a glance
- RxNorm
- 58930
- Generic
- Zyrtec
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Zyrtec is used to treat seasonal allergies (hay fever), perennial allergic rhinitis, and itching associated with chronic urticaria (hives). It provides relief from symptoms triggered by pollen, dust mites, pet dander, and mold.
Zyrtec contains cetirizine, which is a second-generation antihistamine that works by blocking histamine H1 receptors in the body. By preventing histamine from binding to these receptors, it reduces allergic inflammation, itching, and mucus production. Unlike first-generation antihistamines, it has a lower tendency to cross the blood-brain barrier, resulting in less drowsiness for most users.
Zyrtec is available over-the-counter in various forms including tablets, liquid gels, and chewable tablets. While generally well-tolerated, some individuals may experience mild side effects such as drowsiness, dry mouth, or headache. It is important to follow label directions and consult a healthcare provider before use if you have kidney disease or are taking other medications.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy