Serum or Plasma Substance Concentration for Serine Protease Inhibitor (e.g., Alpha-1 Antitrypsin variant or related protease inhibitor)
This test measures the level of a protein that helps protect your lungs and liver from damage caused by enzymes released during inflammation or injury.
["This test helps assess risks for lung diseases like emphysema or liver problems related to protein imbalances."]
Key facts at a glance
- LOINC
- 50075-1
- Short code
- 11DC 1h p 250 ug ACTH SerPl-sCnc
- Synonyms
- 11DC 1h p 250 ug ACTH SerPl-sCnc
- Category
- hormone
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 10
- Ref high
- 60
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Your sample contains a specific type of protein that naturally inhibits enzymes that could harm your body’s tissues. This test quantifies how much of this protein is present in your blood, which can vary depending on genetic factors, health conditions, or medications.
Why It Matters in Your Health
High or low levels of this protein may indicate conditions like genetic disorders affecting lung or liver function, chronic inflammation, or certain metabolic issues. It’s often used alongside other tests to diagnose or monitor these conditions.
Common Reasons for Testing
Doctors may order this test if you have symptoms like persistent coughing, shortness of breath, or liver-related issues (e.g., jaundice, fatigue). It’s also used in research or specialized screening for inherited protein disorders.
Sample Collection and Preparation
A blood sample is drawn from your arm, typically in the morning after fasting. The blood is processed to separate serum or plasma, which is then sent to a lab for analysis. Avoid strenuous activity or certain medications before testing for best accuracy.
Reference range
NCBI: ACTH 10-60 pg/mLN/A
Typically collected in the morning (8-10 AM). Inform your provider if taking steroid medications.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Alpha-1 Antitrypsin or Related Protease Inhibitor Level
Frequently asked questions
How long will results take to get?
What if my results are outside normal ranges?
Do I need to prepare differently if I’m pregnant?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy